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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
)
Found
1
hit in this display
Target
Serine/threonine-protein kinase B-raf [416-766,V600E]
(Homo sapiens (Human))
Beigene
US Patent
Ligand
BDBM186813
(US9670203, Compound 1.5)
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Affinity Data
IC50: 2.20E+3nM
T: 2°C
Assay Description:
Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...
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Target Info
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Ligand Info
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US Patent
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