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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by
ChEMBL
Ligand
BDBM46004
(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of TNAP (unknown origin) using PPi as substrate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by
ChEMBL
Ligand
BDBM46004
(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by
ChEMBL
Ligand
BDBM46004
(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.85E+3nM
Assay Description:
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
Curated by
ChEMBL
Ligand
BDBM46004
(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.51E+3nM
Assay Description:
Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrate
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI