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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM46004(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of TNAP (unknown origin) using PPi as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM46004(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Affinity DataIC50: <100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM46004(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Affinity DataIC50:  1.85E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM46004(5-chloranyl-2-methoxy-N-quinolin-3-yl-benzenesulfo...)
Affinity DataIC50:  4.51E+3nMAssay Description:Inhibition of TNAP (unknown origin) in whole blood using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed