Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50:  80nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of MMP2 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50:  4.56E+3nMAssay Description:Inhibition of MMP13 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MMP14 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MMP1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50278942(CHEMBL499905 | D-2-(4-(but-2-ynyloxy)phenylsulfona...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TACE in mouse Raw264.7 cells assessed as inhibition of LPS-induced TNFalpha production treated 1 hr before LPS challenge measured 4 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed