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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
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Target
Non-specific protein-tyrosine kinase
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50328195
(7-(4-methoxybenzyl)-N-(4-(trifluoromethoxy)phenyl)...)
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Affinity Data
IC50: 9.68E+3nM
pH: 7.5
Assay Description:
In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
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Target
Non-specific protein-tyrosine kinase [T818I]
(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM50328195
(7-(4-methoxybenzyl)-N-(4-(trifluoromethoxy)phenyl)...)
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Affinity Data
IC50: >1.00E+4nM
pH: 7.5
Assay Description:
In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
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Target
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM50328195
(7-(4-methoxybenzyl)-N-(4-(trifluoromethoxy)phenyl)...)
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Affinity Data
EC50: 9.68E+3nM
Assay Description:
Inhibition of Bcr-Abl in mouse BA/F3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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