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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379367
(CHEMBL2011945)
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Affinity Data
IC50: 40nM
Assay Description:
Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379367
(CHEMBL2011945)
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Affinity Data
IC50: 122nM
Assay Description:
Inhibition of Ikkepsilon using 5FAM-AKELDQGSLCTpSFVGTLQ-NH2 as substrate by microfluidic mobility shift assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Aurora kinase B
(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379367
(CHEMBL2011945)
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Affinity Data
IC50: 370nM
Assay Description:
Inhibition of Aurora B kinase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379367
(CHEMBL2011945)
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Affinity Data
IC50: 6.52E+3nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
Astrazeneca R&D Boston
Curated by
ChEMBL
Ligand
BDBM50379367
(CHEMBL2011945)
Copy SMILES
Copy InChI
Affinity Data
EC50: 17nM
Assay Description:
Inhibition of TBK1-mediated NFkappaB activation expressed in ds-RNA activated HEK293 cells coexpressing TLR3 after 4.5 hrs by luciferase reporter gen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI