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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50326939
(1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-met...)
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Affinity Data
IC50: 23nM
Assay Description:
Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluore...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Glucocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50326939
(1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-met...)
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Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50326939
(1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-met...)
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Affinity Data
IC50: >2.00E+3nM
Assay Description:
Binding affinity to progesterone receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled RU-486 by fluorescence po...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50326939
(1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-met...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+3nM
Assay Description:
Binding affinity to mineralocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by flu...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI