Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept

Curated by ChEMBL

LigandBDBM50164904(1-(2,4-Dimethoxy-phenyl)-3-((2R,3R)-2-pyridin-3-yl...)Copy SMILESCopy InChI

Affinity DataKi:  31nMAssay Description:Inhibitory constant against [3H]methyllycaconitine binding towards Nicotinic acetylcholine receptor alpha-7 of rat brain hippocampusMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL

LigandBDBM50164904(1-(2,4-Dimethoxy-phenyl)-3-((2R,3R)-2-pyridin-3-yl...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2; Not significantMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI