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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085]
(Human)
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM162189
(US9682995, 88)
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Affinity Data
IC50: 1.70E+4nM
pH: 8.0
Assay Description:
Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Human)
Bayer Pharma Aktiengesellschaft
US Patent
Ligand
BDBM162189
(US9682995, 88)
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Affinity Data
IC50: >2.00E+4nM
pH: 7.5 T: 22°C
Assay Description:
N-terminally His6-tagged recombinant catalytic domain of human Bub1 (amino acids 704-1085), expressed in insect cells (Hi5) and purified by Ni-NTA af...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI