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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
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Affinity Data
IC50: 1.10E+3nM
Assay Description:
Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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Article
PubMed
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Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70E+3nM
Assay Description:
Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
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Copy InChI
Affinity Data
IC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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PC sid
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PCBioAssay
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Target
Nuclear hormone receptor family member daf-12
(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Transcription factor p65
(Homo sapiens (Human))
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 752nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Nuclear hormone receptor family member daf-12
(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM49484
((4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine | ML...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.75E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI