Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAurora kinase A(Homo sapiens (Human))
S*Bio

Curated by ChEMBL

LigandBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)Copy SMILESCopy InChI

Affinity DataIC50:  42nMAssay Description:Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescenceMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase B(Homo sapiens (Human))
S*Bio

Curated by ChEMBL

LigandBDBM50315835(2-(2,5-dimethoxyphenyl)-N-(6-methyl-3-styryl-1H-in...)Copy SMILESCopy InChI

Affinity DataIC50:  180nMAssay Description:Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI