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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Abbott
Curated by
ChEMBL
Ligand
BDBM50175478
(3-{2-[4-(2,5-dimethoxy-phenyl)-piperazin-1-yl]-eth...)
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Affinity Data
Ki: 24.2nM
Assay Description:
Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Abbott
Curated by
ChEMBL
Ligand
BDBM50175478
(3-{2-[4-(2,5-dimethoxy-phenyl)-piperazin-1-yl]-eth...)
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Copy InChI
Affinity Data
Ki: 50.2nM
Assay Description:
Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI