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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50336585
(3-(4-methoxyphenylthio)-8-oxo-8H-acenaphtho[1,2-b]...)
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Affinity Data
Ki: 151nM
Assay Description:
Displacement of FAM-Bid from human Mcl-1 after 30 mins by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50336585
(3-(4-methoxyphenylthio)-8-oxo-8H-acenaphtho[1,2-b]...)
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Copy InChI
Affinity Data
IC50: 388nM
Assay Description:
Binding affinity to cMcl-1 (residues 171 to 327) (unknown origin) by biotin-Bim displacement based ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50336585
(3-(4-methoxyphenylthio)-8-oxo-8H-acenaphtho[1,2-b]...)
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Copy InChI
Affinity Data
IC50: 833nM
Assay Description:
Binding affinity to N-terminal 8xHis tagged cBcl-XL (unknown origin) expressed in Escherichia coli BL21 (DE3) by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Dalian University Of Technology
Curated by
ChEMBL
Ligand
BDBM50336585
(3-(4-methoxyphenylthio)-8-oxo-8H-acenaphtho[1,2-b]...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 945nM
Assay Description:
Binding affinity to human Bcl-2 (unknown origin) by biotin-Bim displacement based ELISA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI