Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Banyu Tsukuba Research Institute

Curated by ChEMBL

LigandBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)Copy SMILESCopy InChI

Affinity DataIC50:  22nMAssay Description:Antagonist activity at rat mGluR7 expressed in CHO cells assessed as inhibition of LAP-induced intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear receptor subfamily 4 group A member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL

LigandBDBM50196289(6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5...)Copy SMILESCopy InChI

Affinity DataEC50:  4.10nMAssay Description:Activation of Nurr1 expressed in MN9D cells by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI