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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098269(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholi...)
Affinity DataIC50:  104nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098269(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholi...)
Affinity DataIC50:  478nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098269(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholi...)
Affinity DataIC50:  479nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098269(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholi...)
Affinity DataIC50:  1.07E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098269(2-(4'-Methoxy-biphenyl-4-sulfonylamino)-6-morpholi...)
Affinity DataIC50:  1.37E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed