Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Fidelta

Curated by ChEMBL

LigandBDBM188286(US9073941, 605)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Inhibition of KDM4C (unknown origin) using methylated H3 peptide as substrate by chemiluminescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

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In DepthDetails ArticlePubMed
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TargetDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex(Mycobacterium tuberculosis)
Academia Sinica

US Patent

LigandBDBM188286(US9073941, 605)Copy SMILESCopy InChI

Affinity DataIC50: <40nMpH: 7.0Assay Description:Mtb PDH (Lpd+DlaT+AceE) is provided by Dr. Bryk Ruslana. The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (...More data for this Ligand-Target Pair

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UniProtKB/SwissProt
GoogleScholar

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In DepthDetails US Patent
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TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Academia Sinica

US Patent

LigandBDBM188286(US9073941, 605)Copy SMILESCopy InChI

Affinity DataIC50:  70nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI