Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMetabotropic glutamate receptor 1(RAT)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50364719(CHEMBL1951658)Copy SMILESCopy InChI

Affinity DataKi:  17nMAssay Description:Antagonist activity at rat metabotropic glutamate receptor 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50364719(CHEMBL1951658)Copy SMILESCopy InChI

Affinity DataIC50:  6.30nMAssay Description:Antagonist activity at human metabotropic glutamate receptor 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50364719(CHEMBL1951658)Copy SMILESCopy InChI

Affinity DataIC50:  4.62E+3nMAssay Description:Antagonist activity at human metabotropic glutamate receptor 5More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI