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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50170427
((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
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Affinity Data
IC50: 70nM
Assay Description:
Effective concentration at human melanocortin 4 receptor in cAMP release assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50170427
((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 5 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50170427
((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+3nM
Assay Description:
Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50170427
((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.40E+3nM
Assay Description:
Effective concentration against human melanocortin 3 receptor in cAMP release assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50170427
((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 110nM
Assay Description:
Effective concentration at human melanocortin 4 receptor in cAMP release assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI