Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170427((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Affinity DataIC50:  70nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170427((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170427((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of [125I]-NDP- alpha-MSH binding to human melanocortin 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170427((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Affinity DataEC50:  2.40E+3nMAssay Description:Effective concentration against human melanocortin 3 receptor in cAMP release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170427((4R,5S)-4-(4-Fluoro-phenyl)-pyrrolidine-3-carboxyl...)
Affinity DataEC50:  110nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed