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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50:  118nMAssay Description:Inhibition of GFP-tagged human BCRP expressed in MDCK2 cells pre-incubated for 30 mins followed by Hoechst 33342 addition and further incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50:  378nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50:  535nMAssay Description:Inhibition of human DNA polymerase deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50086871(CHEMBL3426388)
Affinity DataIC50:  587nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed