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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetBeta-lactamase(Escherichia coli)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibitory activity against E. coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  7.90E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universit£

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  1.56E+4nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin Carlsberg(Bacillus licheniformis)
TBA

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  1.80E+5nMAssay Description:Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  3.10E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  5.77E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase TEM(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  6.70E+5nMAssay Description:Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataKi:  7.57E+5nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Oxford

LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataIC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26133((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
Affinity DataAssay Description:The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed