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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Beta-lactamase
(Escherichia coli)
Northwestern University Medical School
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 5.90E+3nM
Assay Description:
Inhibitory activity against E. coli AmpC beta-lactamase.
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Target Info
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 7.90E+3nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay
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Target Info
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 1.09E+4nM
Assay Description:
Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
Carbonic anhydrase
(Candida albicans (Yeast))
Universit£
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 1.56E+4nM
Assay Description:
Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assay
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Target
Subtilisin Carlsberg
(Bacillus licheniformis)
TBA
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 1.80E+5nM
Assay Description:
Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentus
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Target Info
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 3.10E+5nM
Assay Description:
Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentus
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Target Info
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 5.77E+5nM
Assay Description:
Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentus
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Target
Beta-lactamase TEM
(Escherichia coli)
TBA
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 6.70E+5nM
Assay Description:
Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli
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Target
Subtilisin BL
(Bacillus lentus)
TBA
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Ki: 7.57E+5nM
Assay Description:
Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentus
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat))
University Of Oxford
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
IC50: 2.00E+3nM
pH: 7.4 T: 2°C
Assay Description:
[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...
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Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human))
Takeda California
Curated by
ChEMBL
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
IC50: 5.01E+3nM
Assay Description:
Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Monoglyceride lipase
(Homo sapiens (Human))
University Of Oxford
Ligand
BDBM26133
((4-methoxyphenyl)boranediol | CHEMBL21427 | Phenyl...)
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Affinity Data
Assay Description:
The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI