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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Metabotropic glutamate receptor 1
(RAT)
Merz Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50296670
(3-(2-chloro-6-methylquinolin-3-yl)-1-(4-methoxyphe...)
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Affinity Data
Ki: >4.00E+4nM
Assay Description:
Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
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Article
PubMed
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Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Merz Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50296670
(3-(2-chloro-6-methylquinolin-3-yl)-1-(4-methoxyphe...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(RAT)
Merz Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50296670
(3-(2-chloro-6-methylquinolin-3-yl)-1-(4-methoxyphe...)
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Copy InChI
Affinity Data
IC50: 2.05E+4nM
Assay Description:
Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI