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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Interstitial collagenase
(Homo sapiens (Human))
Nippon Organon K.K.
Curated by
ChEMBL
Ligand
BDBM50109620
((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
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Affinity Data
Ki: 17.8nM
Assay Description:
Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Nippon Organon K.K.
Curated by
ChEMBL
Ligand
BDBM50109620
((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
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Affinity Data
Ki: 23.2nM
Assay Description:
Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Nippon Organon K.K.
Curated by
ChEMBL
Ligand
BDBM50109620
((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
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Affinity Data
Ki: 24.4nM
Assay Description:
Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 9
(Homo sapiens (Human))
Nippon Organon K.K.
Curated by
ChEMBL
Ligand
BDBM50109620
((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...)
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Copy InChI
Affinity Data
IC50: 2.24E+3nM
Assay Description:
Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI