Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 11 hits in this display
Gag-Pol polyprotein [484-582,I494L,I497V,V499I,D514N,E519D,R541K,D544E,Q553K,N572D,L573M](Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
HIV-1 protease(Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
Ki: 0.546nMAssay Description:HIV protease inhibitor activities were determined by fluorescence resonance energy transfer (FRET) method. Protease substrate, Arg-Glu-(EDANS)-Ser-G...More data for this Ligand-Target Pair
Gag-Pol polyprotein [484-582,I497V,V499I,E519D,G532V,I538V,R541K,D544E,Q553K,V566A,L573M](Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
Ki: 2.04nMAssay Description:HIV protease inhibitor activities were determined by fluorescence resonance energy transfer (FRET) method. Protease substrate, Arg-Glu-(EDANS)-Ser-G...More data for this Ligand-Target Pair
Gag-Pol polyprotein [484-582,I497V,V499I,E519D,R541K,D544E,Q553K,A555V,G557S,I568V,L574M,L573M](Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
Ki: 2.47nMAssay Description:HIV protease inhibitor activities were determined by fluorescence resonance energy transfer (FRET) method. Protease substrate, Arg-Glu-(EDANS)-Ser-G...More data for this Ligand-Target Pair
Gag-Pol polyprotein [484-582,I494L,I497V,V499I,E519D,I534V,R541K,D544E,Q553K,A555V,L573M](Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
Ki: 3.40nMAssay Description:HIV protease inhibitor activities were determined by fluorescence resonance energy transfer (FRET) method. Protease substrate, Arg-Glu-(EDANS)-Ser-G...More data for this Ligand-Target Pair
MDRC4(Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
EC50: 65.7nMAssay Description:Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro...More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-892,N526H,R530K,V566I,I582L,V648I,Q690K,I723V,C750S,T788A,Q795E,T874A,V881I,P882Q](Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
EC50: 22.4nMAssay Description:Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro...More data for this Ligand-Target Pair
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
EC50: 38.4nMAssay Description:Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro...More data for this Ligand-Target Pair
MDR1(Human immunodeficiency virus)Massachusetts Institute Of Technology
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
EC50: 86.9nMAssay Description:Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro...More data for this Ligand-Target Pair
BDBM104108(N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...)
EC50: 47.3nMAssay Description:Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro...More data for this Ligand-Target Pair