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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
11-beta-hydroxysteroid dehydrogenase 1 [24-292,C272S]
(Homo sapiens (Human))
Amgen
Ligand
BDBM32542
(arylsulfonylpiperazine, 14)
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Affinity Data
IC50: 19nM EC50: 456nM
pH: 7.2 T: 2°C
Assay Description:
Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse))
Amgen
Ligand
BDBM32542
(arylsulfonylpiperazine, 14)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI