Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082478(CHEMBL343392 | Sodium; 3-[3-hydroxycarbamoyl-2-(4-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077371(CHEMBL56965 | Sodium; 3-[(R)-3-hydroxycarbamoyl-2-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082478(CHEMBL343392 | Sodium; 3-[3-hydroxycarbamoyl-2-(4-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed