Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAurora kinase B(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL

LigandBDBM50206391(CHEMBL3894492)Copy SMILESCopy InChI

Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase A(Homo sapiens (Human))
Taiwan National Health Research Institutes

Curated by ChEMBL

LigandBDBM50206391(CHEMBL3894492)Copy SMILESCopy InChI

Affinity DataIC50:  480nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI