Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

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TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
The Institute Of Cancer Research

LigandBDBM29709(Pyridoimidazolone, 5i)Copy SMILESCopy InChI

Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The biological activities (IC50s) of the compounds were determined against the B-RAF (V600E) mutant enzyme in vitro. GST-MEK1, B-RAF (V600E), and inh...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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