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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  11nMAssay Description:Inhibition of c-KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  460nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataKd:  960nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)
Affinity DataKd:  58nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed