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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Purdue University
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
Ki: >9.40E+3nM
Assay Description:
Compound was tested for binding affinity using [3H]-MDL-100,907 at 5-hydroxytryptamine 2A receptor sites in rat cortical homogenate.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
IC50: 140nM
Assay Description:
Binding affinity of the compound against 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1D
(GUINEA PIG)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
IC50: 420nM
Assay Description:
Binding affinity of the compound against 5-hydroxytryptamine 1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Serotonin 2 (5-HT2) receptor
(RAT)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
IC50: 680nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
IC50: 1.20E+3nM
Assay Description:
Binding affinity of the compound against 5-hydroxytryptamine 1C receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Affinity Data
IC50: 5.80E+3nM
Assay Description:
Binding affinity of the compound against 5-hydroxytryptamine 1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serotonin 2 (5-HT2) receptor
(RAT)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50081702
(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
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Copy InChI
Affinity Data
IC50: >8.40E+3nM
Assay Description:
Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI