Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  109nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed