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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
University Of Messina
Curated by
ChEMBL
Ligand
BDBM50334182
(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)
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Affinity Data
IC50: 78nM
Assay Description:
Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Aldo-keto reductase family 1 member B1 [K65Q]
(Bos taurus (Cattle))
University Of Messina
Curated by
ChEMBL
Ligand
BDBM50334182
(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)
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Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysis
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI