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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(CHEMBL272036 | N-(3,4-dimethoxybenzyl)-2-(3-methox...)
Affinity DataIC50:  180nMAssay Description:Inhibition of ABCB1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(CHEMBL272036 | N-(3,4-dimethoxybenzyl)-2-(3-methox...)
Affinity DataIC50:  500nMAssay Description:Inhibition of ABCG2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(CHEMBL272036 | N-(3,4-dimethoxybenzyl)-2-(3-methox...)
Affinity DataEC50:  180nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50234488(CHEMBL272036 | N-(3,4-dimethoxybenzyl)-2-(3-methox...)
Affinity DataEC50:  500nMAssay Description:Inhibition of human BCRP pump mediated [3H]mitoxantrone transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed