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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melatonin receptor type 1B
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
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Affinity Data
Ki: 0.110nM
Assay Description:
Binding affinity on human melatonin receptor type 1B stably transfected in human embryonic kidney (HEK 293) cells using 2-[125I]-iodomelatonin as rad...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1B
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.110nM
Assay Description:
Displacement of [125I]2-iodomelatonin from MT2 receptor (unknown origin) expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1A
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21.6nM
Assay Description:
Binding affinity on human melatonin receptor type 1A stably transfected in human embryonic kidney (HEK 293) using 2-[125I]-iodomelatonin as radioliga...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1A
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 22nM
Assay Description:
Displacement of [125I]2-iodomelatonin from MT1 receptor (unknown origin) expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1A
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 138nM
Assay Description:
Intrinsic activity evaluated on [35S]-GTP -gamma-S binding in Chinese hamster ovarian (CHO) cells, stably expressing human Melatonin receptor type 1A
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1B
(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol
Curated by
ChEMBL
Ligand
BDBM50114701
(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.390nM
Assay Description:
Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI