Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50149915(CHEMBL3769669)Copy SMILESCopy InChI

Affinity DataIC50:  631nMAssay Description:Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50149915(CHEMBL3769669)Copy SMILESCopy InChI

Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI