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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Alpha-1A adrenergic receptor
(CALF)
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 0.350nM
Assay Description:
Binding affinity of the compound towards Alpha-1A adrenergic receptor in bovine brainusing [3H]-prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 0.350nM
Assay Description:
Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +++:highly active
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 1.76nM
Assay Description:
Binding affinity of the compound towards Alpha-1A adrenergic receptor in rat hipocampal membranes using [3H]-prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1D adrenergic receptor
(Rattus norvegicus (Rat))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 6.57nM
Assay Description:
Binding affinity of the compound towards Alpha-1D adrenergic receptor in rat brain using [3H]-prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1B adrenergic receptor
(Homo sapiens (Human))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 21.1nM
Assay Description:
Binding affinity of the compound towards Alpha-1B adrenergic receptor hamster smooth muscle using [3H]-prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1B adrenergic receptor
(Rattus norvegicus (rat))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 62.6nM
Assay Description:
Binding affinity of the compound towards Alpha-1B adrenergic receptor in rat liver using [3H]-prazosin as radioligand
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 86.5nM
Assay Description:
Binding affinity of the compound towards Dopamine receptor D2 in rat striatum using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
University Of Camerino
Curated by
ChEMBL
Ligand
BDBM50050915
(CHEMBL72657 | [2-(2,6-Dimethoxy-phenoxy)-ethyl]-((...)
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Affinity Data
Ki: 889nM
Assay Description:
Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor in rat hypocampus membrane using [3H]-8-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI