Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL

LigandBDBM50312556((1R,2R,4S)-2-(6-chloro-5-(3-methoxyphenyl)pyridin-...)Copy SMILESCopy InChI

Affinity DataKi:  0.0190nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex after 4 hrs by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL

LigandBDBM50312556((1R,2R,4S)-2-(6-chloro-5-(3-methoxyphenyl)pyridin-...)Copy SMILESCopy InChI

Affinity DataKi:  558nMAssay Description:Displacement of [3H]iodo-MLA from alpha7 nAChR in rat cerebral cortex after 2 hrs by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI