Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataIC50:  420nMAssay Description:Inhibition of recombinant human CYP1A2 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataIC50:  4.19E+3nMAssay Description:Inhibition of recombinant human CYP2C9 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of recombinant human CYP2D6 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of recombinant human CYP3A4 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of recombinant human CYP2B6 by P450-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataEC50:  5.12E+3nMAssay Description:Agonist activity at CAR LBD (108 to 348 residues) expressed in human HepG2 cells assessed as receptor binding to PGC1alpha by lanthascreenTR-FRET coa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataEC50: >3.50E+3nMAssay Description:Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at AHR expressed in human HepG2 cells after 24 hrs by pXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataEC50:  4.04E+3nMAssay Description:Agonist activity at human CAR3 expressed in African green monkey COS-1 cells cotransfected with RXRalpha after 24 hrs by CYP2B6-luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Palacky University In Olomouc

Curated by ChEMBL
LigandPNGBDBM50185305(CHEMBL3822867)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at VDR expressed in human HuH7 cells after 24 hrs by pDR3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed