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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
IC50: 420nM
Assay Description:
Inhibition of recombinant human CYP1A2 by P450-Glo luminescence assay
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
IC50: 4.19E+3nM
Assay Description:
Inhibition of recombinant human CYP2C9 by P450-Glo luminescence assay
More data for this Ligand-Target Pair
Target Info
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MMDB
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UniProtKB/SwissProt
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Article
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
IC50: 1.73E+4nM
Assay Description:
Inhibition of recombinant human CYP2D6 by P450-Glo luminescence assay
More data for this Ligand-Target Pair
Target Info
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Article
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
IC50: 2.29E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 by P450-Glo luminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Article
PubMed
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Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
IC50: 3.18E+4nM
Assay Description:
Inhibition of recombinant human CYP2B6 by P450-Glo luminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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Target
Nuclear receptor subfamily 1 group I member 3
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
EC50: 5.12E+3nM
Assay Description:
Agonist activity at CAR LBD (108 to 348 residues) expressed in human HepG2 cells assessed as receptor binding to PGC1alpha by lanthascreenTR-FRET coa...
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Target Info
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MMDB
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Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
EC50: >3.50E+3nM
Assay Description:
Agonist activity at PXR expressed in human HepG2 cells after 24 hrs by p3A4-luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
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Target
Aryl hydrocarbon receptor
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
EC50: 2.30E+3nM
Assay Description:
Agonist activity at AHR expressed in human HepG2 cells after 24 hrs by pXRE-luciferase reporter gene assay
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Target Info
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Article
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Target
Nuclear receptor subfamily 1 group I member 3
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
EC50: 4.04E+3nM
Assay Description:
Agonist activity at human CAR3 expressed in African green monkey COS-1 cells cotransfected with RXRalpha after 24 hrs by CYP2B6-luciferase reporter g...
More data for this Ligand-Target Pair
Target Info
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MMDB
KEGG
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antibodypedia
GoogleScholar
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CHEMBL
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In Depth
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Article
PubMed
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Target
Vitamin D3 receptor
(Homo sapiens (Human))
Palacky University In Olomouc
Curated by
ChEMBL
Ligand
BDBM50185305
(CHEMBL3822867)
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Affinity Data
EC50: >3.00E+3nM
Assay Description:
Agonist activity at VDR expressed in human HuH7 cells after 24 hrs by pDR3-luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI