Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetLiver carboxylesterase 1(Oryctolagus cuniculus (rabbit))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi:  72.1nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi:  139nM ΔG°:  -39.1kJ/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi:  1.54E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Mississippi

LigandPNGBDBM22744(1,2-bis(3-methoxyphenyl)ethane-1,2-dione | Benzil-...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed