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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Lipopolysaccharide-induced tumor necrosis factor-alpha factor
(Homo sapiens (Human))
Vtv Therapeutics
US Patent
Ligand
BDBM235362
(US10085990, Example 91 | US9393245, 91)
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Affinity Data
IC50: 1nM
Assay Description:
Samples were tested for TNF as per the manufacturer's instructions (TNF ELISA; R&D Systems, Cat #DY210). The samples were serially diluted with P...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tumor necrosis factor
(Homo sapiens (Human))
Vtv Therapeutics
US Patent
Ligand
BDBM235362
(US10085990, Example 91 | US9393245, 91)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
T: 2°C
Assay Description:
Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at ro...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI