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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Signal transducer and activator of transcription 1-alpha/beta
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
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Affinity Data
IC50: >6.19E+3nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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Target
Signal transducer and activator of transcription 3 [702-738,740-752]
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
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Affinity Data
IC50: 3.09E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
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Target
Bcl-2-like protein 11
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
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Affinity Data
EC50: 2.88E+4nM
Assay Description:
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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PCBioAssay
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Target
Protein RecA
(Mycobacterium tuberculosis H37Rv)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
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Affinity Data
EC50: 1.62E+4nM
Assay Description:
Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Target
Protein RecA
(Mycobacterium tuberculosis H37Rv)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.26E+3nM
Assay Description:
Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
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Target
Matrix metalloproteinase-14 [1-36]
(Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM43507
(4-(4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-p...)
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Affinity Data
EC50: 2.20E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI