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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Replicase polyprotein 1ab
(2019-nCoV)
The State University Of New Jersey
Curated by
ChEMBL
Ligand
BDBM50197349
(CHEMBL3983492 | ebselen derivative 1e)
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Affinity Data
IC50: 256nM
Assay Description:
Inhibition of SARS-CoV-2 papain-like protease preincubated for 60 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Replicase polyprotein 1ab
(2019-nCoV)
The State University Of New Jersey
Curated by
ChEMBL
Ligand
BDBM50197349
(CHEMBL3983492 | ebselen derivative 1e)
Copy SMILES
Copy InChI
Affinity Data
IC50: 256nM
Assay Description:
The inhibitor was screened against recombinant PLproSARS and PLproCoV2 at 37°Cin the assay buffer as described above. For...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI
Target
Replicase polyprotein 1ab
(2019-nCoV)
The State University Of New Jersey
Curated by
ChEMBL
Ligand
BDBM50197349
(CHEMBL3983492 | ebselen derivative 1e)
Copy SMILES
Copy InChI
Affinity Data
IC50: 256nM
Assay Description:
Inhibition of SARS-CoV-2 PLpro
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Replicase polyprotein 1ab
(2019-nCoV)
The State University Of New Jersey
Curated by
ChEMBL
Ligand
BDBM50197349
(CHEMBL3983492 | ebselen derivative 1e)
Copy SMILES
Copy InChI
Affinity Data
IC50: 260nM
Assay Description:
Inhibition of recombinant SARS CoV-2 PL protease incubated for 60 mins by fluorescence based analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Microtubule-associated protein 2
(Homo sapiens (Human))
Wroclaw University Of Technology
Curated by
ChEMBL
Ligand
BDBM50197349
(CHEMBL3983492 | ebselen derivative 1e)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.98E+3nM
Assay Description:
Non-covalent/mixed type inhibition of recombinant human MetAP2 using Met-AMC as substrate preincubated for 30 mins followed by substrate addition by ...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI