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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Affinity Data
Ki: 28.6nM
Assay Description:
Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Affinity Data
Ki: 37.9nM
Assay Description:
Displacement of [3H]8-OH-DPAT from 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Affinity Data
Ki: 329nM
Assay Description:
Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Affinity Data
Ki: 4.80E+3nM
Assay Description:
Displacement of [125I]DOI from 5HT2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Affinity Data
IC50: 440nM
Assay Description:
Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM50343789
(CHEMBL1774385 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
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Copy InChI
Affinity Data
EC50: 134nM
Assay Description:
Agonist activity at 5HT1A receptor assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI