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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Neuromedin-K receptor
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
Ki: 370nM
Assay Description:
Displacement [3H]SB-222200 from of human recombinant NK3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
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Target
Neuromedin-K receptor
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Copy InChI
Affinity Data
Ki: 370nM
Assay Description:
Binding affinity to human NK3 receptor by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
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Target
Substance-P receptor
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding affinity to human NK1 receptor by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
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Target
Neuromedin-K receptor
(Rattus norvegicus)
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
Ki: 3.40E+3nM
Assay Description:
Binding affinity to rat NK3 receptor by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
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Target
Substance-K receptor
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
Ki: 1.30E+4nM
Assay Description:
Binding affinity to human NK2 receptor by radioligand binding assay
More data for this Ligand-Target Pair
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Target
Neuromedin-K receptor
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 180nM
Assay Description:
Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 9.00E+3nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 3.40E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Euroscreen
Curated by
ChEMBL
Ligand
BDBM50341081
((5-(4-chlorophenyl)-1-methyl-1H-pyrazol-3-yl)(4-(2...)
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Affinity Data
IC50: 4.20E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
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