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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
Ki: 0.340nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
Ki: 0.690nM
Assay Description:
Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
Ki: 20.7nM
Assay Description:
Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 27nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2A
(PIG)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
Ki: 330nM
Assay Description:
Displacement of [3H]ketanserin from 5-HT2 receptor in porcine cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
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Article
PubMed
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Target
D(1A) dopamine receptor
(Sus scrofa)
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
Ki: 1.10E+3nM
Assay Description:
Displacement of [3H]SCH 23990 from dopamine D1 receptor in porcine cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
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In Depth
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Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
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Affinity Data
EC50: 1.70nM
Assay Description:
Agonist activity at human dopamine receptor D2long expressed in CHO10001 cells assessed as stimulation of incorporation [3H]-thymidine incorporation
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander-UniversitäT Erlangen-NüRnberg
Curated by
ChEMBL
Ligand
BDBM50132069
(3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pip...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.90nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in CHO dhfr-negative cells assessed as stimulation of [3H]-thymidine incorporation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI