Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent

LigandBDBM92812(Bisanilinopyrimidine, 6e | US9249124, 28)Copy SMILESCopy InChI

Affinity DataIC50:  4nMpH: 7.4 T: 2°CAssay Description:Reactions were carried out at room temperature in 15 mM HEPES buffer (pH 7.4) containing 20 mM NaCl, 1 mM EGTA, 0.02% Tween 20, 10 mM MgCl2, 5% (v/v)...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetAurora kinase A(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent

LigandBDBM92812(Bisanilinopyrimidine, 6e | US9249124, 28)Copy SMILESCopy InChI

Affinity DataIC50:  4nMAssay Description:In vitro enzyme activity assay using Aurora Kinase A. More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI