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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 4.5nM
Assay Description:
Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 76nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 290nM
Assay Description:
Inhibition of FLT3
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 540nM
Assay Description:
Inhibition of PI3Kgamma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 1.00E+3nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 1.10E+3nM
Assay Description:
Inhibition of IRAK4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 1.80E+3nM
Assay Description:
Inhibition of SYK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 2.50E+3nM
Assay Description:
Inhibition of JNK3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: 3.50E+3nM
Assay Description:
Inhibition of JAK2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: >4.00E+3nM
Assay Description:
Inhibition of SRC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
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Affinity Data
Ki: >4.00E+3nM
Assay Description:
Inhibition of ROCK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >4.00E+3nM
Assay Description:
Inhibition of PLK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50313061
((Z)-3-(4-methoxypyridin-3-yl)-4-(2-phenylhydrazono...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >4.00E+3nM
Assay Description:
Inhibition of MET
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI