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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(RAT)
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50002331
(4-[4-(5-Fluoro-4-methoxy-pyrimidin-2-yl)-piperazin...)
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Affinity Data
IC50: 24nM
Assay Description:
Displacement of (+)-[3H]-3-PPP from rat cortical sigma site
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50002331
(4-[4-(5-Fluoro-4-methoxy-pyrimidin-2-yl)-piperazin...)
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Affinity Data
IC50: 180nM
Assay Description:
Inhibition of [3H]WB-4101 binding to rat cortical Alpha-1 adrenergic receptor in vitro
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Bristol-Myers Squibb
Curated by
ChEMBL
Ligand
BDBM50002331
(4-[4-(5-Fluoro-4-methoxy-pyrimidin-2-yl)-piperazin...)
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Affinity Data
IC50: 3.94E+3nM
Assay Description:
In vitro inhibitory against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI