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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
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Affinity Data
Ki: 13nM
Assay Description:
Displacement of radiolabeled T0901317 from LXRbeta LBD (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
Copy SMILES
Copy InChI
Affinity Data
Ki: 136nM
Assay Description:
Displacement of radiolabeled T0901317 from LXRalpha LBD (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
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Affinity Data
IC50: 858nM
Assay Description:
Inhibition of CYP2C9 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
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Affinity Data
IC50: 1.27E+4nM
Assay Description:
Inhibition of CYP2D6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
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Affinity Data
IC50: 1.54E+4nM
Assay Description:
Inhibition of CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-alpha
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
Copy SMILES
Copy InChI
Affinity Data
EC50: 491nM
Assay Description:
Agonist activity at LXRalpha LBD (unknown origin) fused with Gal4-DNA binding domain expressed in HEK293 cells assessed as modulation of receptor tra...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Oxysterols receptor LXR-beta
(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50192760
(CHEMBL3972392)
Copy SMILES
Copy InChI
Affinity Data
EC50: 15nM
Assay Description:
Agonist activity at LXRbeta LBD (unknown origin) fused with Gal4-DNA binding domain expressed in HEK293 cells assessed as modulation of receptor tran...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI