Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of CYP2C9 preincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CYP2D6 preincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP2C9 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 preincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 coincubated with compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin heavy chain isoform 5A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293753(2-(4-(methylsulfonyl)phenylamino)-1-(2-(trifluorom...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed