Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50421275
(CHEMBL2087651)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7nM
Assay Description:
Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells assessed as inhibition of autophosphorylation after 2 hrs by EL...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Activated CDC42 kinase 1
(Mus musculus)
Amgen
Curated by
ChEMBL
Ligand
BDBM50421275
(CHEMBL2087651)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of ACK1 in mouse C8 cells assessed as decrease in cell viability after 20 to 24 hrs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI