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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  100nMAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against 15-lipoxygenase obtained from soybeanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase obtained from potatoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoxygenase(Solanum tuberosum (potato))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:The lipoxygenase inhibitor screening assay detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified lipoxygen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  3.00E+4nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Alberta

LigandPNGBDBM22351(1,3-Diarylprop-2-yn-1-one, 13h | 1-(4-fluorophenyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory activity against ovine cyclooxygenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed